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| Water Retention | |
| Hepatotoxicity | Yes, potential for significant liver injury, requires regular liver function tests |
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| Chemical name | 5-methylisoxazole-4-carboxylic acid 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)butylamide |
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| Dosage (medical) | Typically 100 mg daily for three days, then reduced to 10-20 mg daily |
| Dosage (sports) | |
| Effects | Reduces inflammation and slows disease progression in rheumatoid arthritis and psoriatic arthritis |
| Side effects | Diarrhea, respiratory infections, hair loss, rash, hypertension, and liver toxicity |
| Use in sports | |
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